Analysis of Segmental Duplications and Genome Assembly in the Mouse
نویسندگان
چکیده
منابع مشابه
Analysis of segmental duplications and genome assembly in the mouse.
Limited comparative studies suggest that the human genome is particularly enriched for recent segmental duplications. The extent of segmental duplications in other mammalian genomes is unknown and confounded by methodological differences in genome assembly. Here, we present a detailed analysis of recent duplication content within the mouse genome using a whole-genome assembly comparison method ...
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Primate-specific segmental duplications are considered important in human disease and evolution. The inability to distinguish between allelic and duplication sequence overlap has hampered their characterization as well as assembly and annotation of our genome. We developed a method whereby each public sequence is analyzed at the clone level for overrepresentation within a whole-genome shotgun s...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2004
ISSN: 1088-9051
DOI: 10.1101/gr.2238404